Blood group D antigen content of nucleated red cell precursors

Blood group D antigen content of nucleated red cell precursors.

The D antigen content of nucleated red cell precursors in human bone marrow was estimated using autoradiography and 125I-anti-D. D antigen first appeared in the pronormoblast, and the quantity of antigen progressively increased during red cell maturation. Maximal anti-D binding occurred on mature red blood cells. Pronormoblasts, basophilic normoblasts, polychromatophilic normoblasts, and orthoc...

Autoradiographic estimation of red cell D antigen content using 125I-anti-D and 125I membrane labeling.

Assessment of Umbilical Cord Nucleated Red Blood Cell Count in Discharged and Dead Very Low Birth Weight Infants

Background: Predictive value of the umbilical nucleated red blood cells (NRBCs) at birth for neonatal outcomes has been assessed. Hence, the present study was conducted to compare NRBC between discharged and dead neonates.Methods: This cross-sectional study was performed on preterm newborns with a birth weight of < 1,500 g admitted to the Neonatal Intensive Care Unit of Ghaem Hospital, Ma...

Decreased a Globin mRNA in Nucleated Red Cell Precursors in a Thalassemia

The a thalassemias are associated with a decrease in a chain synthesis. Hemoglobin H (HbH) disease is a moderately severe form of a thalassemia characterized by the production of 5%-20% of HbH, while a thalassemia trait is a milder form of a thalassemia. In two patients with HbH disease, the ratio of a chain synthesis to fi chain synthesis (a/fl ratio) was decreased in both bone marrow cells an...

Decreased a Globin mRNA in Nucleated Red Cell Precursors in a

The a thalassemias are associated with a decrease in a chain synthesis. Hemoglobin H (HbH) disease is a moderately severe form of a thalassemia characterized by the production of 5%-20% of HbH, while a thalassemia trait is a milder form of a thalassemia. In two patients with HbH disease, the ratio of a chain synthesis to fi chain synthesis (a/fl ratio) was decreased in both bone marrow cells an...